Our new book Next-Generation DNA Sequencing Informatics is the first of its kind to address the informatics needs of scientists who wish to take advantage of the explosion of research opportunities offered by new DNA sequencing technologies.
Edited by Stuart Brown, the book includes contributions from researchers at New York University’s Langone Medical Center, which invested heavily and early in next-generation sequencing (NGS) technology and informatics capacity. “In this book, building on our own extensive experience that spans collaborations on more than 30 National Institutes of Health-funded projects, and by critically evaluating and synthesizing the literature in the field, we provide an overview of many core types of next-generation sequencing projects, a discussion of methods embodied in popular software, and detailed descriptions of our own best practice workflows,” writes Brown.
Topics include data visualization, sequence alignment, genome assembly and annotation, variant discovery, RNA-seq, ChIP-seq, and metagenomics, as well as the history of DNA sequencing and informatics. An accompanying website, seqinformatics.com, offers tutorials and resources for NGS. For additional details on the book, click here.