Do you teach a biology or biotechnology course involving genes or genomes? Are you looking to update or refresh the course? Our new book Genome Science contains 19 innovative laboratory exercises for high school and college teaching. The exercises can be used to enhance existing courses, start new courses, or support student research projects.
Developed by the world-renowned DNA Learning Center at Cold Spring Harbor Laboratory, the exercises illustrate key concepts of genome biology in humans, plants, and the worm C. elegans. “Genome Science aims to help beginners use modern tools to explore the unseen world of genes and genomes,” write David Micklos, Bruce Nash, and Uwe Hilgert, the book’s authors. “All labs stress the modern synthesis of molecular biology and computation, integrating in vitro experimentation with in silico bioinformatics.”
Molecular techniques such as polymerase chain reaction (PCR), DNA sequencing, and RNA interference (RNAi) are used to analyze DNA mutations, detect epigenetic modifications, silence genes, identify transposon insertions, detect genetically modified foods, and trace evolutionary histories. Computational tools are used to search, view, annotate, align, and compare DNA sequences. The labs are complemented by illustrated introductory text that provides an historical and conceptual framework. The book is complete with advice for instructors, laboratory planning guidelines, recipes for solutions, and answers to student questions.
For more information about the book, click here.