Cellular health depends on the proper expression, folding, and degradation of thousands of proteins. Protein Homeostasis, recently released by CSHL Press, covers the mechanisms by which cells ensure efficient functioning of the proteome, and the diseases that result when these processes go awry.

Protein Homeostasis addresses the remarkable story of the life of proteins,” write the editors, Richard Morimoto, Dennis Selkoe, and Jeffrey Kelly. The contributors examine the physical biochemistry of protein folding; the cellular compartments involved in protein quality control; the various chaperones, translocation machineries, proteasomes, and autophagic activities; and the role of proteostasis in aging and disease.

Protein Homeostasis is invaluable for molecular and cellular biologists, as well as medical scientists wishing to understand the pathological consequences of and potential therapies for protein homeostasis deficiencies in common human diseases. For details on the book, click here.