The extracellular matrix (ECM) plays a role in the function of virtually all cells, regulating cellular morphology, adhesion, cell migration, cell proliferation, and apoptosis. Extracellular Matrix Biology, a new book from CSHL Press, covers ECM composition and function, as well as its roles in development, physiology, and pathology.

“We have endeavored to illustrate the manifold aspects of ECM biology,” write the editors Richard Hynes and Kenneth Yamada. Contributors discuss the various ECM proteins and proteoglycans, ECM receptors such as integrins, and the signaling pathways that mediate the effects of the ECM on cells. They also describe ECM functions in specific biological contexts, including angiogenesis, hemostasis, and thrombosis.

“We hope that this collection of reviews by experts in the field will serve to promote research leading to discoveries and applications based on improved understanding of the ECM,” write Hynes and Yamada. Extracellular Matrix Biology is an indispensable reference for cell biologists and all those interested in exploring the myriad functions of the ECM.  For more details on the book, click here.